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Gilda Radner was born on June 28, 1946 in Detroit, Michigan where she grew up. She was the youngest child of two children. She had an older brother who was five years her senior. Upon graduating high school, young Radner attended the University of Michigan where she majored in drama. She dropped out of college and moved to Toronto, Canada. Her first acting part was in the stage play "Godspell." She then worked in the weekly syndicated "National Lampoon Radio Hour." From there, she worked in the Second City troupe in Toronto, Canada. From there Miss Radner joined the original cast of Saturday Night Live where she was a featured actor. She created several characters with her most popular being Roseanne Roseannadanna. She worked consistently for ten years. She made over ten movies and appeared on television shows during her career. She also appeared on "The Muppet Show" in 1978

She met Gene Wilder while she was married to G.E. Smith whom she was wed to in 1980. Wilder on the other hand, had already been divorced twice and in no hurry to get into another serious relationship. In 1982, Gilda filed for divorce and it only took six months for her divorce to become final. At the time, Miss Radner was living in Connecticut while Wilder was living in Los Angeles, California. The two friends got to know each other and the two of them lived together for the next two and a half years. She turned down acting parts so she could be near Gene. Eventually the couple wed on September 18, 1984 by the mayor of a small village in the south of France. Their efforts to have children failed. Miss Radner had two miscarriages and her health seemed to be failing. In 1986, Gilda was diagnosed with ovarian cancer. For two years, she endured cancer therapy, which consisted of surgery, chemotherapy and radiation treatments. Through this journey, Miss Radner discovered The Wellness Community – a non-profit organization that has a program that helps cancer patients and their family the tools to participate in their cancer treatments. They also offer Tai Chi classes, massages and programs for everyone. They also offer emotional support.

On May 20, 1989, Miss Radner lost her battle against ovarian cancer in Los Angeles, California where her and Mr. Wilder were living at the time of her death. She is buried at the Long Ridge Cemetery in Stamford, Connecticut.